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IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3) is a synthetic peptide engineered to enhance the anabolic effects of natural IGF-1 while significantly extending its half-life

However, the expression of GPX3 is inhibited by promoter hypermethylation, resulting in the loss of cellular antioxidant capacity

Gai Z, Wang T, Visentin M, et al

Additionally, translating these findings into clinical therapies, such as microbiota-based treatments or lipid-targeting interventions, poses a significant challenge

TCP-25 not only exhibits broad-spectrum antimicrobial activity but also binds bacterial endotoxins (e.g., lipopolysaccharide) neutralizing their inflammatory effects