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These experimental compounds work through various proposed mechanisms, such as stimulating melanocortin receptors in the brain, but lack robust clinical evidence and carry significant safety concerns

Such hyperexcitability can disturb brainstem excitatoryinhibitory balance, contributing to respiratory and motor dysfunction (Zhong et al., 2017)
A systematic review of oral retinoids for treatment of acneiform eruptions induced by epidermal growth factor receptor inhibitors
