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Recent studies support the hypothesis that autoimmune thyroiditis is tumorigenic in itself and that through excitation of the TSH receptor, HT-associated hypothyroidism may also contribute to tumor growth (Boi et al

This leads to the generation of cytotoxic hydrogen peroxide (H 2 O 2 , i.e

[DOI] [PMC free article] [PubMed] [Google Scholar] 207.Dissayabutra T., Kalpongnukul N., Chindaphan K., et al

Mitochondrial membrane potential (m), a key indicator of mitochondrial integrity, becomes depolarized under oxidative assault, impairing ATP synthesis via oxidative phosphorylation (OXPHOS)