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Enzyme localization, properties, and functions The enzymes of the ascorbateglutathione cycle are localized in different intracellular compartments (Table 1)

Recent reports demonstrated that GSH depletion triggers ferroptosis in some cell types 18

doi: 10.1016/j.bbi.2010.10.015

Epub 2021 Mar 19

Comorbid conditions such as cognitive impairment, epilepsy, psychiatric diseases, and behavioral symptoms such as impaired social communication, repetitive behaviors, lack of interest in the environment, nutritional disorders, gastrointestinal diseases and abnormal (dysbiotic) states, sleep disorders, and dysmorphism are frequently encountered in individuals with ASD