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Failure of phospholipid hydroperoxide glutathione peroxidase expression in oligoasthenozoospermia and mutations in the PHGPx gene

Verhoef et al, 1997b

In whole-cell current clamp experiments, hyperpolarizing or depolarizing current pulses (500 ms, from 10 to 30 pA in 5-pA steps) were injected into neurons to determine input resistances or trigger action potentials

CRISPR-dCas9 epigenome editing platforms employ catalytically dead Cas9 fused to epigenetic effectors ( TET1 for active demethylation, DNMT3A for targeted methylation) without DNA breaks, enabling precise chromatin manipulation

When patients pre- and post-treatment characteristics were compared, patients with the TT genotype did not show any significant improvement