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The oxidized protein tyrosine derivative, 3-NT, provides a stable biochemical footprint of oxidative protein damage and has been found to be elevated in plasma of children with autism in a previous study

Zinc deficiency exacerbates these processes by upregulating molecules like vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1), facilitating monocyte attachment and intensifying vascular inflammation and AS progression [475, 476]

It is likely that RISK-SAFE pathways represent an oversimplified framework

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in Nutraceutical Beverages: Chemistry, Nutrition, and Health Effects ACS Symp