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In this section, we wish to refer to the mechanism of reaction between heme (a rather vital molecule for life [189]), and particular its oxidized forms (hematin and hemin (ferric chloride heme)) and GSH as well as the consequences of this conjugation on the cytotoxic actions of the endogenous, electrophile, free heme

The elimination of many xenobiotic compounds can be accomplished through conjugation with Glutathione followed by secretion from cells (such as mercury and persistent organic pollutants)

Luikenhuis et al., 1998

Patients who are taking retinoid-derived medications may be building up a toxic amount of vitamin A in their bodies without knowing it

Tian J, Kaufman DL