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Description
Although superoxide (O 2 .- ) initiated cascades of reactions are important in clearing foreign pathogens, largely within the safe confines of the phagocytic vacuole, sustained NADPH oxidase (NOX) activation is considered to result in adverse effects on the host [3]
doi: 10.1016/j.molimm.2016.01.008 54 SonDOLiuWLiXPrudhommeGJWangQ

Phospho-peptide enrichment was performed using TiO 2 (Titansphere Phos-TiO Bulk 10 um, GL Science), ratio of beads to sample 10:1, mixed for 30 minutes at room temperature in 80% acetonitrile, 6% trifluoroacetic acid, 5 mM monopotassium phosphate, 20 mg/mL 2.5-dihydroxybenzoic acid

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Ki and IC50 values are 111.6 M and 52.3 M, respectively
