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Many of these diseases are related to the process of atherosclerosis

In a cohort of 57 ALL patients, the incidence of TP53 mutation, one TP53 allele deletion, and promoter hypermethylation was 8.8%, 7.5%, and 32% respectively [11]

Deficient glutamate clearance drives neuronal damage in neurotoxic disorders such as WernickeKorsakoff encephalopathy or hepatic encephalopathy 137,138,139 , whereas diminished K + buffering together with insufficient glutamate clearance leads to spreading depression, migraine and epilepsy 140,141,142

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[Google Scholar] 163.van Winden EC