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Perluigi M, Tramutola A, Pagnotta S et al (2020) The BACH1/Nrf2 axis in brain in down syndrome and transition to Alzheimer disease-like neuropathology and dementia

It is secreted by I-cells in the duodenal and small bowel mucosa in response to protein and fat, with its main effects on the liver, gallbladder, pancreas and, interestingly, central nervous system (CNS)

Additionally, exploring combination therapies that can synergize with folate receptor targeting could improve outcomes

In particular, unstable hemoglobins autoxidize and precipitate, forming the hemichromes, containing all forms of hemoglobins and leading to the release of heme [238,239]

Development of an antibody fused with an antimicrobial peptide targetingPseudomonas aeruginosa:a new approach to prevent and treat bacterial infections