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The -chain (69 kDa) comprises an N-terminal (N) hairpin-loop and 4 kringle domains (K1K4) while the -chain (3234 kDa) has a serine proteinase homology (SPH) domain (Holmes et al., 2007)

The AZIN2 gene is located on chromosome 1p35.1 and is composed of 16 exons that generate 18 alternatively spliced mRNAs that collectively encode six distinct protein isoforms

Meanwhile, immunofluorescence (Figure 6B) results revealed that anwuligan treatment promoted the nuclear localization of Ctnnb1 in HFSCs, and this effect was inhibited by the Wnt pathway inhibitor XAV939