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Differentiation of LS patient derived iPSCs into neural lineage in both 2D neural cultures and 3D organoids revealed a consistent trend across all LS cerebral organoids, which exhibited impaired growth at various time intervals

The versatility of the FolTAC-dual platform positions it as a promising candidate for next-generation targeted therapies, offering a pathway to develop higher-order degraders and combinatorial treatment strategies for complex diseases beyond cancer