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Irisin has been shown to alleviate PD symptoms by increasing the expression of neuroprotective factors such as BDNF and PGC-1 17

USA 102 , 93419346 (2005)

5.6 Food and Nutritional Supplements 5.6.1 Tripeptides as Functional Food Components for Health Promotion and Disease Prevention The gut hormones glucagon-like peptide 1 (GLP-1), oxyntomodulin (OXM), and peptide tyrosine tyrosine (PYY) are elevated following gastric bypass surgery

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13 Understanding that both location and size of GA lesions can play a role in determining whether a treatment like pegcetacoplan would be functionally beneficial for a patient is critical for clinicians, because this information can influence which treatment options would have greater efficacy over others in certain situations