glutathione metabolism and parkinson& 39 Decreases Parkinsonism‐Induced Ferroptosis Oxidative Stress Through the Inhibition of the TRPM2 Channel in Neuronal Cells - Güzel - 2025 - Pharmacology Research & Perspectives Metabolic Dysfunction in Parkinson's Disease:

Vitamin C l cu ni gia hai hot cht: Vitamin C va thit yu cho qu trnh tng hp collagen, va h tr ti to glutathione t dng oxy ha (GSSG) tr li dng hot tnh (GSH)

doi: 10.1016/S0140-6736(21)00569-9

In pancreatic cancer, LAT2 ( SLC7A8 ) was shown to decrease gemcitabine sensitivity by regulating glutamine-dependent mTOR activation to promote proliferation and inhibit apoptosis (Feng et al., SLC7A5 ) and LAT2 ( SLC7A8 ) have been discovered, which facilitate the clinical application of system L transporters (Table 1

Conversely, COX5a upregulation facilitated neuronal survival post-oxygen-glucose deprivation (OGD), decreasing apoptosis and notably increasing the length of neuronal dendrites (Jiang et al., 2020)

doi: 10.1073/pnas.1101143108 187 YangYCaoLGaoHWuYWangYFangFet al