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To examine the involvement of MT-1/2 in the neuroprotective effects of mirtazapine, Mir-NCM-ACM was preincubated with a mouse anti-MT-1/2 monoclonal antibody (DakoCytomation, Glostrup, Denmark) (1:500) for 1 h at 25 C and then added to the neuronal cultures

Huang M, Long J, Yao Z, Zhao Y, Zhao Y, Liao J, et al
Risque de cancer (angiogense)

Its activity has been reported to be both reduced and elevated in the depressive state (103, 104) but appears to be predominantly decreased in bipolar mania (105, 106)
