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A protein-restricted diet may enhance the blood pressure-lowering and antiproteinuric effect of angiotensin-receptor blockers (ARBs), a standard therapy for hypertension and kidney diseases that cause proteinuria (Bellizzi 2013)

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additionally NAD + can be generated in the mitochondria from NMNAT3 80 , whose activity has been shown to be required in cells 77 , but dispensable in vivo as NAD + can be replenished through other pathways such as import from the cytosol 81

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Gut microbial factors predict disease severity in a mouse model of multiple sclerosis