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Larazotide functions by tightening these loose junctions, effectively closing the gaps in the gut lining

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doi: 10.3389/fimmu.2021.635869 14 World Health Organization

While promoting angiogenesis and decreasing inflammation through a number of mechanisms, it supports cell migration, differentiation, and cytoskeletal remodeling

In a double-blind randomized trial, patients with ALD treated with 150 mg metadoxine for three months showed a considerable decrease in transaminase and -GT levels, as well as a reduction of steatosis, after the first month of treatment [164]