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This study reported differential effects of melatonin as 0.1 mg, 0.3 mg, and 3 mg on several sleep parameters in 30 insomniac subjects who were over 50 years of age [18]

In pre-clinical research, it is primarily studied for its effects on gastrointestinal healing, tendon and ligament repair, vascular growth (angiogenesis), and potential neuroprotective properties

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327 For instance, excessive or improper mechanical loading can disrupt collagen fiber alignment and lead to maladaptive cellular responses, increasing the risk of injury
