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Hemodynamic improvement of pulmonary arterial hypertension after bariatric surgery: Potential role for metabolic regulation

To date, three isoforms of Trx have been identified in mammalian cells: Trx1 (cytosolic), Trx2 (mitochondrial), and SpTrx (spermatozoa cells) ( 2 O 2 and lipid hydroperoxide, in addition to TrxS 2

They showed that although TSPO expression increased significantly in the mouse models of each condition, it did not increase in humans

These compounds exhibit biological activities in vitro , such as neuroprotection, antioxidant properties, and -glucuronidase inhibition

Additional file 4 (download PDF : Manual drug repurposing chart