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GHK-Cu is among the peptides removed from Category 2 in 2026 and is used in some compounded and topical formulations

As some peptides modify cell growth or repair, there is a theoretical risk of encouraging undesired cell proliferation

Therefore, the immediate presentation of adverse effects and the parallel therapeutic effects might suggest an essential cause-consequence chain of events of Budd-Chiari and BPC 157 in rats, and in particular, a relation to the liver as the prime organ affected[26-32] and failure of its circulation

But that has not stopped them from gaining a foothold in the burgeoning marketplace for wellness hacks and alternative remedies