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Key points to keep in mind: Injectable glutathione is not a proven anti-aging treatment

Chin J Anaesthesiology

Combined curcumin and exercise intervention in hyperlipidemic rats downregulates pyroptosis genes (NLRP3, ASC (Apoptosis-associated speck-like protein containing a CARD), caspase-1) by inhibiting TLR4/MyD88/NF-B (Toll-like receptor 4/Myeloid differentiation factor 88/Nuclear factor kappa-B) signaling and reducing serum IL-1 (Ramos et al., 2016)

Diabetes Care 21 , 278282 (1998)

GPX4 differs from the other GPX family members in terms of its monomeric structure, a less restricted dependence on glutathione as reducing substrate, and the ability to reduce lipid-hydroperoxides inside biological membranes