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Developing therapeutic strategies based on cell-state-specific vulnerabilities remains an important goal in oncology Tumor cell populations with specific metabolic affinities and potentially unique therapeutic vulnerabilities have been recently identified in glioma (Garofano et al, 2021

Injections were performed under a microscope, with the needle tip positioned at an approximate 30 angle to the cecal wall, ensuring that the needle tip penetrated the cecal wall to a depth of 4 mm while avoiding bleeding or cellular reflux

Several high-impact publications have demonstrated a positive association between the development of irAEs and anti-tumour responses to ICIs, across tumour types 2,3

In the body, it serves as a means of transport for the long-chain fatty acids into the mitochondria, the site of fat burning, where vital energy is obtained from the fats

Melatonin and erastin emerge synergistic anti-tumor effects on oral squamous cell carcinoma by inducing apoptosis, ferroptosis, and inhibiting autophagy through promoting ROS