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Another option is mechanical stimulation therapy, based on the sensitivity of the Piezo1 channel to mechanical stimulation, specific physical therapy or mechanical stimulation can be developed to regulate the activity of microglia by altering the mechanical properties of the microenvironment in the CNS, thereby promoting the clearance of A plaques

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Then the show started

While strongly supported by literature and observed biochemical correlations, the proposed mechanistic roles for these lipids in LID pathology should be considered hypothesis-generating rather than definitive