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The HPA axis includes the Hypothalamus (brain region), Pituitary (a gland in the brain), and Adrenals (produces adrenalin and cortisol)

When these radicals accumulate in the skin, they can inflict premature aging and various skin ailments by damaging cellular components such as DNA and lipids

Research evidence 1 suggests the molecular mechanism behind balding is a gradual replacement in the scalp of large, pigmented hairs (terminal hairs) by barely visible, depigmented hairs

The telogen phase is also when new hairs start to form in follicles that have just released hairs during the catagen phase

this is of potential importance not only for the understanding of ASD pathogenesis but also for supporting the diagnosis of ASD and monitoring the disease progression