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3,5-T2-an endogenous thyroid hormone metabolite as promising lead substance in anti-steatotic drug development

The essential nature of the dendritic arbor as a scaffold for synaptic contacts between neurons suggests that, although continued treatment with ALC appeared unable to ameliorate synaptic signalling deficits that develop later in the course of the symptoms, the underlying structure and connectivity to support improved cognitive function are present

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And talking to very great colleagues of yours, Bret, that work with you guys together and that work in the whole metabolic psychiatry field

This differential regulatory mechanism provides a critical theoretical foundation for targeted therapeutic interventions