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Overall effect: B complex may help ease anxiety, improve focus, and reduce mental fatigue, especially during periods of high stress or hormonal fluctuations

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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

In this open-label, randomized, controlled trial, 1,323 men and women with a mean age of 83 were either switched from warfarin to a DOAC (662 patients) or left on warfarin (661 patients)

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