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In 1991, primary structure studies revealed that PHGPX was a new selenoprotein distinct but related to GPX-1, allowing PHGPX to be considered a new member of the glutathione peroxidase family [62]

Consult your physician before use if you are pregnant, nursing, taking medication, or have a medical condition

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However, it should be noted that Nrf2 does not regulate the expression of any autophagy-related genes, suggesting that Nrf2 may not directly activate autophagy but indirectly facilitates autophagy activation and degradation in cardiomyocytes (Wang et al., 2014)

Takeaway summary: EIOS can have either beneficial or detrimental effects on force production, recovery, muscle adaptations, and endurance-related performance outcomes, depending on the level of ROS/RNS production from exercise or training bout