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The present review aims to provide an overview of the existing literature assessing the relationships between OCM nutrients status as well as related genetic variation and risk of DM in the context of DM pathology

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Genistein, a phytoestrogen and HIF-1 inhibitor, has shown promise in the treatment of colorectal cancer when combined with bevacizumab [92]

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3.3.3.3 Inhibition of the JAK-STAT signaling pathway The janus kinase/signal transducer and activator of tranions (JAK/STAT) is a common signaling pathway for transducing signals from various cytokines, which widely regulate cell growth, differentiation, inflammation, apoptosis, and other mechanisms