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However, some studies have shown that even in the absence of Lactobacillus , asymptomatic healthy women may have uterine microbiota dominated by genera such as Pseudomonas , Acinetobacter , Vagococcus , and Sphingobium 14 , suggesting that non- Lactobacillus -dominated microbiota may also be considered normal in the absence of pathological signs

Research suggests that NRF2 may play a role in promoting skin epidermal barrier formation and enhancing the differentiation of keratinocytes [38, 39]

In this regard, it is feasible to use bioactive phytochemicals to target dysregulated cellular signaling pathways and provides a promising and low-cost opportunity to treat patients in low- and middle-income countries (LMICs) as the cancer incidence and mortality rates are disproportionately high among the population [146]

Cotticelli, M

Dandurand KR, Stennett DJ