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4.4 Maternal RPM supplementation and offspring performance Considering that embryonic development is the period of extensive epigenetic reprogramming, maternal nutrition during the periconceptional and early pregnancy stages plays a crucial role in establishing the molecular and physiological foundations for fetal growth and long-term offspring performance

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doi: 10.1038/bjc.2012.260 89 MatsudaN.SatoS.ShibaK.OkatsuK.SaishoK.GautierC

Mol Cell 48:900913 Finkelstein JD, Kyle WE, Martin JJ (1975) Abnormal methionine adenosyltransferase in hypermethioninemia

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