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Additionally, the abundance of Citrobacter farmeri , Syntrophaceticus schinkii (He et al., 2022), Bacteroidetes and Elusimicrobia (Zhao et al., 2020) are increased in DN patients with higher UACR, whereas the abundance of Firmicutes, Bacteroidetes, Bacteroides (Tao et al., 2019) and Actinobacteria (Zhao et al., 2020) are decreased

Bovine serum albumin is used as a standard

We utilize small-batch synthesis, which allows for meticulous oversight at every step

sFRPs have a Netrin-related motif in the C-terminal region, WIF has a WIF domain in the C-terminal region, and both bind to Wnt proteins, thereby inhibiting Wnt signalling

the physician determines whether the combined approach is appropriate and how to structure each component Convenience preference: patients who strongly prefer not to self-inject and whose indication is compatible with oral delivery