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Because RNR is the rate-limiting step in de novo pyrimidine biosynthesis, inhibition could create a deoxyribonucleotide pool imbalance
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Another BBB-crossing molecule with HGF-like activity, BB3, was employed in pre-clinical models of stroke, showing good functional improvements (Prat et al., 1998
Histopathological analysis reveals that SAC attenuates mucosal damage and inflammatory infiltration (Fig
