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Karel Zinek (Neurosanatio s.r.o., Litomyl)

Because of the communication between CNS and non-neuronal cells, Glu concentrations and receptor expression in peripheral blood may indicate pathophysiological changes in the CNS

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This study analyzed the gene expression (or epigenetics) in the iTregs (in vitro Tregs) and showed that vitamin C enhances the activity of the TET protein enzymes through de-methylation, making these cells more similar to the mature, properly functioning Tregs in the body which regulate autoimmunity