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Background Cobalamin (vitamin B 12 ) deficiency is common in many low and middle-income countries

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Muscles dont use energy properly, nerves dont transmit signals efficiently, immunity weakens, and mental clarity drops

Meta-Analysis of Randomized Controlled Trials & Observational Studies on Homocysteine Although two randomized controlled trials (RCTs) explored the association between homocysteine levels and Autism Spectrum Disorder (ASD), the sample size (k = 2) did not meet the minimum threshold for formal meta-analytic synthesis