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1 Introduction Ischemic stroke refers to a central nervous system disorder caused by impaired blood supply, leading to ischemic and hypoxic necrosis of brain tissue ( CIRI is a critical link in ischemic stroke, involving highly complex pathological processes, amobg which oxidative stress and neuroinflammation playing pivotal roles ( Sweet Tea (ST), also known as Lithocarpus Polystachyus Rehd., is an ethnobotanical medicine primarily found in Guizhou Province, China, and various provinces south of the Yangtze River ( 2 Materials and methods 2.1 Materials The following reagents and antibodies were used in this study: Enzyme-linked immunosorbent assay (ELISA) Kits from Shanghai Renjie Biotechnology Co., Ltd.: IL-6 (RJ15478), IL-18 (RJ15463), IL-1 (RJ15465), TNF- (RJ16622), Interferon- (IFN-, RJ15676), Lactate dehydrogenase (LDH, RJ16172), ROS (RJ15780), Superoxide dismutase (SOD, RJ16691), Malondialdehyde (MDA, RJ15503), Glutathione (GSH, RJ29397)

Both in vivo and in vitro studies report improvements in motor behavior, restoration of dopaminergic neurons, and reductions in oxidative and neuroinflammatory damage

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