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The typical composition of gut microbiota in healthy individuals primarily includes the phyla Bacteroidetes and Firmicutes , accounting for over 90% of the total bacteria, as well as Actinobacteria , Proteobacteria , and Verrucomicrobia [131]

It has been reported that TGF-induced EMT could increase the stemness and PD-L1 expression on cancer cells, contributing to 5-FU resistance in CRC (Soundararajan et al., 2019

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Higher total GSH contents increased antioxidative protection and electron consumption in Soldanella alpina and Ranunculus glacialis, which in turn enhanced thermotolerance (Laureaua et al