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Plants such as bracken ferns are problematic while toxicity symptoms vary widely based on dose, duration, and species of affected animals these plants contain thiaminases, and thiamine deficiency has been noted in sheep grazing on the plants in Australia

In the Wnt signaling pathway, expression levels of Wnt-10a , Wnt-10b , LRP6 , Lef1 , and -catenin were comparable in the KO and control group