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Environ Toxicol Pharmacol 20(1):99106 Acknowledgements The research is supported by generous fund from Jordan University, Research Deanship

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Natural killer cells NK cells are innate-like lymphocytes with cytotoxic properties that recognize and eliminate invading tumor cells and virus infected cells, while simultaneously produce diversified pro-inflammatory cytokines or chemokines to recruit and activate other immune cells (82, 83)

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We demonstrate that HHEX is a bona fide target gene of the androgen receptor and is highly expressed in the male adrenal, which allows for the repression of female-biased transcriptional programs

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