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Description
A cholestatic liver pattern (e.g., direct bilirubin, ALP, GGT) points to obstruction and can accelerate imaging or biliary drainageoften days sooner than watchful waiting

A., Vijay, S., Walter, J
Raman Spectrosc

In short, it causes tissue buildup that creates pressure on the eyes, causing them to protrude and feel irritated
IHD : 20-50% dialyzable
