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Mitochondrial network determines intracellular ROS dynamics and sensitivity to oxidative stress through switching inter-mitochondrial messengers

The -butyrobetaine dioxygenase enzyme, as well as the first enzyme of carnitine synthesis (trimethyllysine hydroxylase, encoded by the TMLHE gene), are members of the large family of 2-oxoglutarate and ferrous (Fe 2+ ) iron-dependent dioxygenases

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