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Taxonomic profiling of samples was performed using MetaPhlAn 4 (Version 4.1.1) with standard bacterial, viral, and eukaryotic databases [12]

Ma and Li, 2018), as it has been shown to be essential for converting dietary compounds into TMA in gnotobiotic mice and human studies (Wang et al., 2011

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A study on the efficacy and safety assessment of propionyl-L-carnitine tablets in treatment of intermittent claudication

Since lipoic acid synthase was found in mammalian mitochondria [119], and lipoic acid (LA) reversed age-associated mitochondrial decay [82, 120], it is reasonable to hypothesize that the supplemented acetylcarnitine exerts part of its protective effect via providing acetyl groups for LA synthesis within the mitochondria