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Circulatory system Heart injury (e.g., caused by myocardial infarction, I/R, or anthracycline-based chemotherapy) is associated with an increased ferroptotic response with reduced GPX4 and increased iron accumulation

While comprehensive cost-effectiveness analyses are limited, silymarin is often considered an economically viable option due to its availability and relatively low cost compared to some pharmaceutical treatments

Improves recovery after exercise

J Neurosci 23:26272633 Rao SD, Weiss JH (2004) Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis
Iron accumulation and increased lipid peroxides are key indicators of ferroptosis (Fig
