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Acetyl-l-carnitine restores synaptic transmission and enhances the inducibility of stable LTP after oxygen-glucose deprivation

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These studies are designed to evaluate metabolic signaling behavior and cellular energy dynamics , not therapeutic outcomes

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Therefore, improving the glucose metabolic pathway and stabilizing the carnitine palmitoyltransferase-1 and -2 (cPT1/cPT2) mediated -oxidation of high-energy generating pathway are necessary for neuronal protection in alcoholics

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Targeting these mechanisms may result in novel therapeutic approaches aimed at developing the means of effective prevention and treatment of the core ASD symptoms [11]

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