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What they found: Dose-dependent stimulation of type II collagen (up to 2.5 baseline at 100 nM) Stimulation of aggrecan (up to 1.8 baseline) Inhibition of MMP-13 by ~40 % Partial protection against IL-1-induced matrix degradation Why it matters: It opened a completely new research area for AOD-9604 beyond lipolysis

HoloTC accounts for 520% of total transcobalamin which is made in the ileal enterocytes from intracellularly synthesized transcobalamin and absorbed vitamin B12

B12 Injections: Are they more effective than supplements

doi: 10.1016/j.dld.2006.01.014