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3b,c and Extended Data Fig

Interestingly, the combination of trifluoperazine and cyclosporine prevents the opening of the mitochondrial permeability pore caused by the glycochenodeoxycholate (Gores et al., 1998)

Sorafenib analogue, SC-60, has been reported to reduce TNBC cell viability and induced apoptosis by downregulating phosphorylated STAT3 expression in both a dose- and time-dependent manner

The moderate suppression of the TCA cycle and OXPHOS reduces mitochondrial ROS production and inhibits cell death [71]

The discovery of these genes resulted in the clarification of molecular pathways and the involvement of oxidative stress in the pathogenesis of PD
