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however, its functional characterization remains less defined and necessitates further scientific investigation to elucidate its biological contributions

It is known that amino acid conjugation of exogenous carboxylic acids occurs in a twostep process (Reilly et al., 2007)

Special emphasis should be placed on elucidating the dual regulatory mechanisms of ammonia metabolism in CAR-T therapy: maintaining appropriate ammonia levels in the early phase to activate RUNX2-mediated T-cell function, while reducing lysosomal pH via agents such as C381 in the later phase to delay T-cell exhaustion (172)

Managing side effects, having a clear idea of who should not use these supplements, and relying on trusted medical advice are all important steps

Arch Biochem Biophys 1993;300:13741