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Below, linkers employing these various release strategies will be discussed for each cytotoxin class since the few linker-drug motifs that have been successful have repeatedly been used for other antibodies

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Nutrients, 2020

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However, further work is required to standardise synthesis approaches, define safety profiles, and validate efficacy in physiologically relevant models to support future clinical translation

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15 , opioids increase A-a gradients by impairing ventilation-perfusion ratios in the lungs (ventilation-perfusion mismatch)

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Retrieved 21 January 2021

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