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Below, linkers employing these various release strategies will be discussed for each cytotoxin class since the few linker-drug motifs that have been successful have repeatedly been used for other antibodies

Nutrients, 2020

However, further work is required to standardise synthesis approaches, define safety profiles, and validate efficacy in physiologically relevant models to support future clinical translation

15 , opioids increase A-a gradients by impairing ventilation-perfusion ratios in the lungs (ventilation-perfusion mismatch)

Retrieved 21 January 2021
