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ALCAR and LC are naturally produced in the body and occur naturally in the diet, usually when we eat animal protein

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Importantly, of all the metabolites that significantly distinguished +ADT from ADT group, the only metabolite that significantly correlated with PROMIS-SRI sleep impairment T -scores was androsterone sulfate, which is a metabolic endpoint marker of the effectiveness of ADT in reducing circulating androgens (Chi et al., 2020)