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High-dose oral supplements (often 10002000 micrograms daily) or intramuscular injections (typically 1mg hydroxocobalamin) used to treat pernicious anaemia or deficiency states can temporarily elevate serum levels

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Evidence reviews for risk factors and symptoms and signs for vitamin B12 deficiency: Vitamin B12 deficiency in over 16s: diagnosis and management: Evidence review B

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These studies used doses ranging from 1 mg per day to 30 mg per day administered through various routes (subcutaneous, oral, and intranasal)

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