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For this, a T-union was installed in the capillary between the analytical column and the fluorescence detector

While all groups experienced some decline in FEV1 over 52 weeks, the 25-mg dose limited this decline to just 24 mL compared to 62 mL with placebo, a difference that reached statistical significance ( 6.1.3.3 Safety profile and tolerability Throughout the 52-week treatment period, brensocatib demonstrated a reassuring safety profile

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